Daneshfard, Babak, Yekta, Nafiseh Hosseini, Khoshdel, Alireza et al. · Complementary therapies in medicine · 2019 · DOI
This study tested whether a plant supplement called Jadwar could reduce fatigue in healthy university students. Sixty-four students took either a Jadwar capsule or a placebo (dummy pill) for 15 days, and researchers measured their fatigue using a questionnaire before and after. The Jadwar group reported significant improvements across all types of fatigue measured, while the placebo group saw much smaller changes.
While this study examined only healthy individuals rather than ME/CFS patients, it provides preliminary evidence that Jadwar may have anti-fatigue properties worth investigating in clinical populations. For ME/CFS researchers, understanding botanical agents that modulate fatigue perception could inform future mechanistic studies and complementary approaches in severely fatigued populations.
This study does not establish that Jadwar is effective in ME/CFS patients or other disease-related chronic fatigue conditions. The study population consisted of healthy students reporting normal fatigue, not pathological fatigue from disease. The findings cannot demonstrate mechanism of action or whether benefits would persist beyond 15 days of use.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
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