Kossaify, Antoine, Kallab, Kamal · Turk Kardiyoloji Dernegi arsivi : Turk Kardiyoloji Derneginin yayin organidir · 2013 · DOI
This study examines why people faint or feel faint due to problems with their autonomic nervous system—the part of your nervous system that controls heart rate, blood pressure, and breathing automatically. The authors review how fainting episodes are connected to several conditions that ME/CFS patients often experience, including migraines, dizziness upon standing, rapid heartbeat with position changes, and chronic fatigue syndrome. They discuss how autonomic dysfunction may explain these related conditions.
ME/CFS patients frequently experience autonomic dysfunction symptoms including orthostatic intolerance, POTS-like symptoms, and syncope/pre-syncope. This review connects these seemingly separate symptoms to a common underlying mechanism—ANS dysfunction—which may help explain why ME/CFS patients often have multiple overlapping conditions and could guide future diagnostic and treatment approaches.
This review does not establish causal mechanisms through new experimental evidence; it synthesizes existing literature. It does not prove that ANS dysfunction is the primary driver of ME/CFS or that treating ANS dysfunction will cure chronic fatigue syndrome. The study also does not provide prevalence data or quantify the strength of association between NCS and chronic fatigue syndrome.
About the PEM badge: “PEM required” means post-exertional malaise was an explicit required diagnostic criterion for participant inclusion in this study — not that PEM was studied, observed, or discussed. Studies using criteria that do not require PEM (e.g. Fukuda, Oxford) are tagged “PEM not required”. How the atlas works →
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