E2 ModeratePreliminaryPEM ✗Cross-SectionalPeer-reviewedMachine draft
Awareness and Perception of Myalgic Encephalomyelitis and Chronic Fatigue Syndrome Among Pain Specialists: A Questionnaire-Based Study.
Uygun, Gürsan Güneş, Gözükızıl, Salim Taner, Bilen, Ayşegül · Cureus · 2025 · DOI
Quick Summary
This study asked pain doctors in Turkey about their knowledge of ME/CFS and how they evaluate and treat patients with the condition. The results show that many pain specialists aren't familiar with ME/CFS, and some hold misconceptions—like thinking it's a type of depression or that intense exercise will help. This matters because pain doctors could potentially help ME/CFS patients, but they need better education about the condition first.
Why It Matters
Pain specialists represent an underutilized clinical resource for ME/CFS symptom management, yet significant knowledge gaps and misconceptions exist in this specialty. Identifying these gaps is essential for developing targeted education and referral pathways that could improve multidisciplinary care. This study provides evidence-based rationale for educational interventions in pain medicine.
Observed Findings
- Only 39.6% of pain specialists surveyed had heard of myalgic encephalomyelitis.
- Approximately 37.7% of participants believed ME/CFS is a subtype of depression.
- Over half of participants (50.9%) agreed that chronic fatigue improves with intense aerobic exercise.
- 65.9% of physicians stated they rarely or occasionally considered the relationship between fatigue and orthostatic intolerance when evaluating patients.
- When considering ME/CFS diagnosis, 32.1% most frequently referred patients to physical medicine and rehabilitation departments.
Inferred Conclusions
- Pain specialists in Turkey lack sufficient awareness and accurate knowledge of ME/CFS, with significant misconceptions about its relationship to depression and the appropriateness of aerobic exercise.
- Physicians who were unaware of ME/CFS nomenclature and those who disregarded dysautonomic components were more likely to endorse harmful treatment recommendations.
- Standardized clinical guidelines and targeted education for pain specialists are needed to improve ME/CFS recognition and management.
- Pain medicine may be an underutilized specialty for ME/CFS management, particularly for widespread pain symptoms, if specialists receive adequate training.
Remaining Questions
What This Study Does Not Prove
This study does not establish the prevalence of ME/CFS awareness globally or in other countries, nor does it demonstrate whether improving pain specialists' knowledge actually improves patient outcomes. The questionnaire-based design cannot determine causation or the actual clinical behaviors of physicians (only their stated beliefs). Results are specific to Turkish healthcare context and may not generalize internationally.
Tags
Symptom:Unrefreshing SleepOrthostatic IntolerancePainFatigue
Method Flag:No ControlsSmall SampleExploratory Only
Metadata
- DOI
- 10.7759/cureus.81030
- PMID
- 40264626
- Review status
- Machine draft
- Evidence level
- Single-study or moderate support from human research
- Last updated
- 8 April 2026